PubFacts Sign Up Information

Last Updated:

5/10/2020

Site Encrypted:

Yes

Site Category:

Email Verified:

VISIT SITE VIEW PRIVACY POLICY VIEW TERMS OF SERVICE

25/100

Data Held

Email Address

Password

Your Name

First Name, Last Name

Your Address

Post-Registration Data

We are still gathering data about this website

Validation

This site did not show evidence of storing passwords in plaintext.

This site does allow secured connections (https)

This site did show a clear way to unsubscribe from their emails

This site does verify your email address.

Membership Emails

Below is a sample of the emails you can expect to receive when signed up to PubFacts.

Emily Jones

Dear Emily Jones,

Thank you for registering with PubFacts!

Your account for Emily Jones has been activated, and can be viewed at https://www.pubfacts.com/author/Emily+Jones.

Please note that updates to your profile are being reviewed by administrators, and will be made live within 24 hours.

To make changes to your author profile page, you may log in any time at https://www.pubfacts.com/login.

Update Profile

VIEW PUBLIC PROFILE


PubFacts.com \| 3423 Piedmont Rd NE, Atlanta, GA 30305

You are receiving this email because you registered to update this author's profile page. Your email has not been shared. The goal of PubFacts to make the world's scientific research easy to locate, access, and collaborate on.

Emily Jones

Key Metrics for this week:

- Your PubFacts Author profile page was viewed 117 times .
- Your publications have been viewed a total of 2018 times.
- Your articles have been mentioned in 895 non-journal sources such as blogs, news articles, and social media mentions, including:

?????????????????????????????????????
Gigazine
"?????????????????? ?????????? ?? ??????? ???????????????????????????????????????????????????????????????????????????????????????? Want to strengthen your immune system? Consider your feelings https://www.inverse.com/mind-body/why-emotions-affect-the-i."
Chronic Family Stress and Adolescent Health: The Moderating Role of Emotion Regulation.
April 29, 2020 EST

See all recent activity

Update Profile

View All Metrics

My PubFacts Profile Twitter Facebook YouTube

You are receiving this email because you registered to update this author''s profile page. Your email has not been shared. The goal of PubFacts to make the world''s scientific research easy to locate, access, and collaborate on.

Manage email update settings | Unsubscribe

Emily Jones

Vote on May''s Featured Article to Display on Homepage

Dear Emily,

Hundreds of PubFacts Members like you have created our new Article Showcase pages (create your own Showcase - it''s free), and we''ve selected two of our favorites, below.

Place a vote below to select which article should be featured on the PubFacts.com home page, and receive 25 PubFacts points, which can be used to showcase your work throughout PubFacts:

Dr Vankadari Naveen
Monash University

The structural and molecular dynamics studies unravel the structure of novel coronavirus

Vote for
Article 1

Yasir Raouf
University of Toronto Mississauga

Advances in covalent kinase inhibitors

Vote for
Article 2

Article 1:
The structural and molecular dynamics studies unravel the structure of novel coronavirus
Dr Vankadari Naveen

Overview
#COVID-19 or SARS-CoV-2 differs in its protein sequence with other SARS coronavirus. The study shows how this new virus camouflages in human though its unique glycosylation of spike glycoprotein. The study also finds human CD26 as a new target for this coronavirus for cell adhesion & hijacking.

The recent outbreak of pneumonia-causing COVID-19 pandemic is an urgent global public health issue with an increase in mortality and morbidity. The structures of COVID-19 spike glycoprotein in both closed (ligand-free) and open (ligand-bound) conformation open the arena of viral infection. While designing antibodies, the glycosylation pattern of virus need to be considered or the antibodies are useless. The structural and molecular dynamic studies show new human target for this virus and abet in finding new therapeutic to block the interaction between the virus and human CD26 a key immunoregulatory factor for cell adhesion and virulence.
-Dr Vankadari Naveen

Article 2:
Advances in covalent kinase inhibitors
Yasir Raouf

Overview
Over the past decade, covalent kinase inhibitors (CKI) have seen a resurgence in drug discovery. Covalency affords a unique set of advantages as well as challenges relative to their non-covalent counterpart. After reversible protein target recognition and binding, covalent inhibitors irreversibly modify a proximal nucleophilic residue on the protein via reaction with an electrophile. To date, the acrylamide group remains the predominantly employed electrophile in CKI development, with its incorporation in the majority of clinical candidates and FDA approved covalent therapies. Nonetheless, in recent years considerable efforts have ensued to characterize alternative electrophiles that exhibit irreversible or reversibly covalent binding mechanisms towards cysteine thiols and other amino acids. This review article provides a comprehensive overview of CKIs reported in the literature over a decade period, 2007-2018. Emphasis is placed on the rationale behind warhead choice, optimization approach, and inhibitor design. Current FDA approved CKIs are also highlighted, in addition to a detailed analysis of the common trends and themes observed within the listed data set.

This comprehensive review details the last 10-years of kinase-targeting covalent inhibitors, consolidating all published inhibitors within this period. It provides a focus on electrophilic warhead development, scaffold design, metabolic stability and pharmacodynamics. In addition, to achieve further insight into covalent strategies, the review includes a detailed data analysis section regarding the chemical and physical properties of CKIs. This illuminate the trends which underpin their positive and negative attributes. This analysis may inform and accelerate current and future programs utilizing a covalent approach in drug discovery or chemical biology
-Yasir Raouf

Thank you for your contributions to science,
The PubFacts Team

My PubFacts Profile Twitter Facebook YouTube

Manage email update settings | Unsubscribe

Emily Jones

Key Metrics for this week:

- Your PubFacts Author profile page was viewed 92 times .
- Your publications have been viewed a total of 1978 times.
- Your articles have been mentioned in 62 non-journal sources such as blogs, news articles, and social media mentions, including:

Tweet by
Early development of infants with neurofibromatosis type 1: a case series.
December 31, 1969, 7:00 pm EST

See all recent activity

Update Profile

View All Metrics

My PubFacts Profile Twitter Facebook YouTube

Manage email update settings | Unsubscribe

Emily Jones

Dear Emily Jones,

Our system has detected 2 new publications on PubMed which appear to have been authored by you, but not yet added to your PubFacts profile page.

Review All New Publications

You can now connect your profile with your ORCID iD

Recent publications found:

The Uptake, Trafficking, and Biodistribution of Generated Outer Membrane Vesicles.
Emily J Jones, Catherine Booth, Sonia Fonseca, Aimee Parker, Kathryn Cross, Ariadna Miquel-Clop?s, Isabelle Hautefort, Ulrike Mayer, Tom Wileman
Front Microbiol 2020 6;11:57. Epub 2020 Feb 6.
February 2020 | 3.941 Impact Factor

Social brain activation during mentalizing in a large autism cohort: the Longitudinal European Autism Project.
Carolin Moessnang, Sarah Baumeister, Julian Tillmann, David Goyard, Tony Charman, Sara Ambrosino, Simon Baron-Cohen, Christian Beckmann, Sven B?lte
Mol Autism 2020 Feb 22;11(1):17. Epub 2020 Feb 22.
February 2020 | 5.486 Impact Factor

Emily Jones | School of Nursing

United States

Review All New Publications

VIEW PUBLIC PROFILE


PubFacts.com \| 3423 Piedmont Rd NE, Atlanta, GA 30305

Emily Jones

Increase the impact of your publications by creating Showcase pages.

Dear Emily,

We''ve added new tools to PubFacts, allowing you to make your published research stand out. It''s free and easy - here''s how it works:

First, Visit your Publications Page and press " Showcase this Article" to transform your existing publication into a Showcase (see example), including an easy to understand summary, imagery, and display of related social and industry discussions.

Add Publication Showcase Now

Thank you for your contributions to science,
The PubFacts Team

My PubFacts Profile Twitter Facebook YouTube

Manage email update settings | Unsubscribe

Data Name	Data Type	Options
	Text Box
First name	Text Box
Last name	Text Box
Password	Text Box
Email	Text Box
	checklist

Start Searching Today!

PubFacts Sign Up Information

Email Address

Password

Your Name

Your Address

Post-Registration Data

Validation

Membership Emails

Key Metrics for this week:

Key Metrics for this week:

Key Metrics for this week:

Key Metrics for this week:

Key Metrics for this week:

Key Metrics for this week:

Add your Twitter username to earn publication views.

Vote on April''s Featured Article to Display on Homepage

Key Metrics for this week:

Key Metrics for this week:

Key Metrics for this week:

Vote on May''s Featured Article to Display on Homepage

Key Metrics for this week:

Increase the impact of your publications by creating Showcase pages.

Comments about pubfacts

Recently added URLs

Top 10 Search URLs

Top 10 Categories