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Jon Davis:
I believe that you would serve as an excellent reviewer of the manuscript, "South East Asian Medicinal Plants with Angiotensin Converting Enzyme (ACE) Inhibition Properties," which has been submitted to Pharmacognosy Journal. The submission''s abstract is inserted below, and I hope that you will consider undertaking this important task for us.
Please log into the journal web site by 2020-07-12 to indicate whether you will undertake the review or not, as well as to access the submission and to record your review and recommendation.
The review itself is due 2020-07-17.
Submission URL: https://www.phcogj.com/submissions/index.php/phcogj/reviewer/submission?submissionId=635&reviewId=747&key=789U8Nzm
Thank you for considering this request.
Mohammed Khalid
Khalid4411@gmail.com
"South East Asian Medicinal Plants with Angiotensin Converting Enzyme (ACE) Inhibition Properties"
This article aims to provide summary on medicinal plants in the South East Asian countries that have angiotensin-converting enzyme (ACE) inhibitory activity, an activity that is therapeutically useful for treating hypertension. This review paper is a result of extensive searches via electronic database platforms, including Pubmed, Google Scholar, Scopus and Science Direct with the keyword search terms: ACE enzyme, South East Asia countries, plants and extracts. As a result, 34 articles on ACE inhibition activity of 76 South East Asian medicinal plants were found and further reviewed. Several plants from Malaysia (Chassalia curviflora, Citrus hystrix, Murraya koenigii, Senna garrettiana), Indonesia (Gnetum Gnemon, Momordica charantia, Nasturtium officinale, Peperomia pellucida, Pereskia saccharose) and Thailand (Mammea siamensis) were found to exhibit strong ACE inhibitory activity in vitro. Bioactive compounds such as 3',4', dihydroxy-3-5 dimethoxy flavone-7-O-?-rhamnose and quercetin-3-O-glucoside showed the highest potency in exhibiting the ACE inhibition activity in this review. In conclusion, this review suggest for an in-depth investigations on the potent crude extracts for the potential development of complementary herbal medicines as well as on the potent ACE inhibitor compounds for further development as new ACE inhibitor candidates for hypertension therapy.
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